Vibegron

Urinary Incontinence Products · Beta-3 agonist

Indications

Overactive bladder with symptoms of urge urinary incontinence, urgency and urinary frequency with or without benign prostatic hyperplasia (BPH).

Dosage

Adults: 1 tab of 75 mg once daily. Children: Not recommended.

Adverse Effects

Headache, UTI, nasopharyngitis, diarrhoea, nausea, upper RTI.

Risk Factor (Pregnancy/Lactation)

Pregnancy: No evidence of risk in humans. Lactation: Caution advised or effect undetermined. Contraindications: End-stage renal disease with or without haemodialysis. Severe hepatic impairment. Precautions: Monitor for urinary retention esp in patients with bladder outlet obstruction or those taking muscarinic antagonist medications for OAB.

Interactions

Digoxin.

Advice to Patient

Swallow whole tab with water. Tab may be crushed and mixed with applesauce. Report immediately if angioedema associated with upper airway swelling occurs.

Pharmacokinetics

Metabolism: Hepatic. Half-life elimination: 30.8 hrs. Time to peak, plasma: 1-3 hrs. Excretion: Faeces (approx. 59%). Urine (20%).

Brands with this active ingredient

• Virbeg

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.