Ursodeoxycholic Acid

Cholagogue & Hepatic Preps · Bile acid

Indications

Dissolution of radiolucent gallstones.

Dosage

Adults: Gall stones: 8-12 mg/kg daily in two divided doses after meals; one dose always after evening meal. Continue treatment until two successive cholecystogram or ultrasound fail to detect gallstones. Biliary cirrhosis: 12-16 mg/kg daily in three divided doses. If liver function improves after 3 months, total daily dose may be given as a single evening dose. Children: Not recommended.

Adverse Effects

Diarrhoea.

Risk Factor (Pregnancy/Lactation)

Contraindications: Radio-opaque stones, non-functioning gallbladder. Women if not on contraceptives, lactation.

Interactions

Oral contraceptives, oestrogens, fibrates, cholestyramine, colestipol, charcoal, aluminium hydroxide antacids.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.