Thiethylperazine
Antiemetic & Gastroprokinetic · Phenothiazine
Indications
Nausea, vomiting; vertigo; motion sickness.
Dosage
In acute case: Adults: 6.5 mg by IM inj or slow IV. Prevention of post-operative vomiting: Adults: 6.5 mg IM half an hr before the end of operation. Children: Not recommended.
Administration
Inject IM deeply into large muscle mass, patient should be lying down & remain so far at least 1 hour after administration; although not generally recommended, thiethylperazine can be given as an IV infusion over 15-30 min should not be given IV push; SC administration not recommended.
Adverse Effects
CNS disturbances. Anticholinergic effects. ECG and endocrine changes, allergic effects and extrapyramidal symptoms occur rarely at low dosage.
Risk Factor (Pregnancy/Lactation)
Pregnancy: Contraindicated in pregnancy. Lactation: Caution advised or effect undetermined. Contraindications: Severely depressed or comatose states. Precautions: Liver dysfunction. Cardiovascular disease. Bone marrow depression.
Interactions
CNS depressants, alcohol, analgesics, antihypertensives, antidepressants, anticonvulsants, antidiabetics.
Advice to Patient
Take rest or do not change position for 1 hour after taking medication. Contact prescriber if CNS reactions, decreased urine output or vision changes occur. Avoid using alcohol. Avoid dangerous activities. Use sunscreen and avoid direct sunlight to prevent photosensitivity. Periodic eye examination is necessary for patients on long term therapy.
Brands with this active ingredient
Compiled by Healify Pharmacy from published drug references. How we compile it →
Always consult a pharmacist or doctor.