Testosterone Undecanoate

Androgen · Androgen

Indications

Male hypogonadism and osteoporosis due to androgen deficiency.

Dosage

Adults: Initially 3-4 daily for two to three wk, adjusting to 1-3 daily according to response. Children: Not applicable.

Adverse Effects

Female: Amenorrhoea and other menstrual irregularities. Male: Gynaecomastia, excessive frequency and duration of penile erections, inhibition of testicular function, testicular atrophy, impotence.

Risk Factor (Pregnancy/Lactation)

Contraindications: Carcinoma of the male breast or prostate, hypercalcaemia, impaired liver function. Precautions: Cardiac, hepatic or renal insufficiency, epilepsy, migraine, hypertension. Large and repeated doses in puberty may cause premature epiphyseal closure and stop linear growth. Hepatic adenocarcinoma may develop with prolonged use. In women high doses long term therapy produces virilism including irreversible voice deepening.

Interactions

In diabetic patients the metabolic effect of androgen may decrease blood glucose and insulin or hypoglycaemia agent requirements.

Pharmacokinetics

Absorption: Varies according to the formulation. Oral formulation is best absorbed with meal containing at least 30 gm of fat. Excretion: Urine (~90%). Faeces (6%).

Brands with this active ingredient

• Andrex

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.