Silodosin

BPH & Drugs for Urinary Retention · Selective alpha-1 blocker

Indications

To treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH).

Dosage

Adults: BPH: 8 mg once daily with meal. Renal impairment: (CrCl 30-50 mL/min): 4 mg once daily. Children: Not recommended.

Adverse Effects

Retrograde ejaculation, diarrhoea, dizziness, orthostatic hypotension, headache, nasopharyngitis, nasal congestion.

Risk Factor (Pregnancy/Lactation)

Contraindications: CrCl <30 mL/min, severe hepatic impairment (child-pugh score >10), concomitant use of CYP3A4 inhibitors or P-glycoprotein inhibitors.

Interactions

Amprenavir, atazanavir, clarithromycin, indinavir, delavirdine, fosamprenavir, saquinavir, telaprevir, itraconazole, telithromycin, ketoconazole, nefazodone, ritonavir, posaconazole, nelfinavir, voriconazole, conivaptan, boceprevir.

Advice to Patient

Take with or without meals. Inform ophthalmologist that you are taking silodosin if you have to undergo any eye surgery.

Brands with this active ingredient

• Sildat
• Sildin
• Sildoso
• Silodact
• Silorap
• Siloton
• Soliriz

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.