Secnidazole

Amoebicide · Nitroimidazole

Indications

Amoebic dysentery, hepatic amoebiasis, trichomoniasis. Bacterial vaginosis in adult women.

Dosage

Amoebic dysentery: Adults: 2000 mg as a single dose. Children: 30 mg/kg body wt. as a single dose. Hepatic amoebiasis: Adults: 1500 mg daily in one or more doses for 5 days. Children: 30 mg/kg body wt. daily in one or more doses for 5 days. Trichomoniasis: Adults: 2000 mg as a single dose. Sexual partner should be given same dose. Bacterial vaginosis: Adults: 2000 mg as a single dose.

Adverse Effects

GI disturbance, blurred tongue, unpleasant taste.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Precautions: Alcohol during treatment. History of blood disorder.

Interactions

Disulfiram, alcohol.

Pharmacokinetics

Absorption: Oral: Rapidly and completely absorbed. Metabolism: Hepatic. Half-life elimination: 17 hrs. Time to peak, plasma: 4 hrs. Excretion: Urine (approx. 15% of single 2 gm oral dose).

Brands with this active ingredient

• A-Sec
• Dysen
• Ganidal
• Liviat
• Orasecan
• Rosdol
• Secazole
• Secdel
• Secna
• Secnaz
• Secnidal
• Secnirox
• Secnisyd
• Secnomin
• Secondax

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.