Rupatadine

Antihistamine, Systemic · H1 receptor antagonist

Indications

Symptomatic relief of allergic rhinitis, urticaria.

Dosage

Tab: Adults and children over 12 years: 10 mg once daily. Syp: Children: Wt <25 kg: 2.5 mL once a day. Wt >25 kg: 5 mL once a day.

Adverse Effects

Asthaenia, less commonly pyrexia, irritability, myalgia, arthralgia, increased appetite.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Hepatic impairment, renal impairment. Precautions: Susceptibility to QT-interval prolongation (including cardiac disease and hypokalaemia). Elderly.

Pharmacokinetics

Onset of action: 1-2 hrs. Duration of action: Antihistaminic activity: 24 hrs. Absorption: Rapidly absorbed from the GI tract. Metabolism: Hepatic. Half-life elimination: 4.04-6.07 hrs. Time to peak, plasma: 0.75-1 hr. Excretion: Faeces (60.9%). Urine (34.6%).

Brands with this active ingredient

• Alripin
• Rupasaf
• Rupataget
• Rupazon

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.