Propyphenazone and Caffeine

Non-narcotic Analgesic · Pyrazolone/Xanthine

Indications

Pain of different origin.

Dosage

Adults: 1-2 tab 2-4 times daily. Max 4 tab daily. Children: Not recommended.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Precautions: Avoid regular use as analgesic.

Pharmacokinetics

PROPYPHENAZONE: Metabolism: Via demethylation. Time to peak, plasma: 30 mins. Excretion: Urine (mainly). CAFFEINE: Metabolism: Hepatic. Half-life elimination: Neonates: 72-96 hrs. Children >9 mths and Adults: 5 hrs. Time to peak, serum: Oral: Within 30 mins-2 hrs. Excretion: Neonates =1 mth: 86% excreted unchanged in urine. Infants >1 mth and Adults: In urine, as metabolites.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.