Proglumetacin

Anti-rheumatic, Systemic · Indoleacetic acid

Indications

Painful joint and rheumatic disorders: arthritis, chronic progressive poly-arthritis, acute articular rheumatism, osteoarthrosis, spondylarthritis acute gouty arthritis. Muscular sprains strains adjuvant in distortions and fractures. Extra- articular and peri-articular affections.

Dosage

Adults: Initial: 450-600 mg daily in 2 divided doses at meals for 2 wk. Maintenance: 300-450 mg daily in 2 divided doses at meals. Children: Not recommended.

Adverse Effects

Gastro-intestinal bleeding, persistent headache (discontinue if occur). Corneal deposits, retinal disturbances (perform periodic eye tests on long term use).

Risk Factor (Pregnancy/Lactation)

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Active peptic ulcer, history of GIT lesions, aspirin or anti-inflammatory induced allergy. Precautions: Renal or hepatic impairment, monitor on long term therapy, heart failure, elderly, CNS disorders.

Interactions

Salicylates, anticoagulants, lithium, corticosteroids, diuretics, beta-blockers, probenecid, quinolones.

Pharmacokinetics

Metabolism: Hepatic.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.