Prednisolone, Neomycin and Polymyxin B, Eye

Corticosteroid Combinations, Eye · Aminoglycoside/Antibacterial/Corticosteroid

Indications

Topical bacterial infections caused by sensitive organisms and associated with inflammatory and/or allergic conditions of the eye.

Dosage

Drop: Adults & Children: 1 or 2 drops every 3-4 hourly.

Advice to Patient

Wash hands properly before use. To instill medication into eyes, tilt head back, look upward, instill drops or apply thin layer of ointment inside lower eyelid. Close eye and roll eyeball in all directions. Do not blink for 30 seconds. Apply gentle pressure to inner corner of eye for 30 seconds. Contact prescriber if there is eye pain, changes in vision, no improvement or worsening of condition. Avoid touching tip of applicator with eye. Avoid prolonged use. Do not use any other eye preparation for atleast 10 minutes. Do not share medication with anyone else. Wear sunglasses when in sunlight to prevent photosensitivity.

Pharmacokinetics

PREDNISOLONE: Absorption: Absorbed through aqueous humor. Systemic absorption rarely occurs. Metabolism: Locally metabolized. Small amount absorbed into systemic circulation is metabolized via hepatic route. Half-life elimination: 3-4 hrs. Excretion: Urine (mainly). Faeces. POLYMYXIN B: Absorption: Not absorbed significantly into the aqueous humor of the eye even when inflammation is present. Excretion: Urine (60%). NEOMYCIN: Metabolism: Not metabolized. Excretion: Urine.

Brands with this active ingredient

• Biopred

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.