Prednisolone and Sulphacetamide, Eye

Corticosteroid Combinations, Eye · Antibacterial/Corticosteroid

Indications

Infected ocular inflammation.

Dosage

DROP: Adults & Children: 1-2 drops three or more times daily. OINT: Adults & Children: Apply ½ inch ribbon to lower conjunctival sac 3-4 times daily and 1-2 times at night.

Adverse Effects

Rise in intra-ocular pressure, corneal thinning, cataract, fungal infection.

Risk Factor (Pregnancy/Lactation)

Contraindications: Viral, fungal, tuberculous or purulent infections of the eye. Dendritic ulcer. Glaucoma. Soft contact lenses. Precautions: Prolonged use in pregnancy or infants. Glaucoma.

Advice to Patient

Wash hands properly before use. To instill medication into eyes, tilt head back, look upward, instill drops or apply thin layer of ointment inside lower eyelid. Close eye and roll eyeball in all directions. Do not blink for 30 seconds. Apply gentle pressure to inner corner of eye for 30 seconds. Contact prescriber if there is eye pain, changes in vision, no improvement or worsening of condition. Avoid touching tip of applicator with eye. Avoid prolonged use. Do not use any other eye preparation for atleast 10 minutes. Do not share medication with anyone else. Wear sunglasses when in sunlight to prevent photosensitivity.

Pharmacokinetics

PREDNISOLONE: Absorption: Absorbed through aqueous humor. Systemic absorption rarely occurs. Metabolism: Locally metabolized. Small amount absorbed into systemic circulation is metabolized via hepatic route. Half-life elimination: 3-4 hrs. Excretion: Urine (mainly). Faeces. SULPHACETAMIDE: Absorption: Penetrates into ocular tissues and fluids. Metabolism: Hepatic. Half-life elimination: 7-13 hrs. Excretion: Urine.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.