Pegaptanib

Other Ophthalmologicals · Vascular endothelial growth factor inhibitor

Indications

Treatment of neovascular (wet) age-related macular degeneration (AMD).

Dosage

By intravitreal injection, 300 mcg once every 6 wk into the affected eye.

Adverse Effects

Rhinorrhoea; headache; eye pain, anterior chamber inflammation, raised intra-ocular pressure, punctate keratitis, vitreous floaters, cataract, conjunctival and retinal haemorrhage, local oedema, conjunctivitis, corneal dystrophy, dry eye, endophthalmitis, eye discharge, eye irritation, macular degeneration, mydriasis, periorbital haematoma, photophobia, flashing lights, vitreous disorders; less commonly vomiting, dyspepsia, palpitation, chest pain, hypertension, aortic aneurysm, influenza-like symptoms, nightmares, depression, back pain, asthenopia, blepharitis, corneal deposits, vitreous haemorrhage, chalazion, retinal exudates, eyelid ptosis, decreased intra-ocular pressure, injection-site reactions, retinal detachment, occlusion of retinal blood vessels, ectropion, eye movement disorder, pupillary disorder, iritis, optic nerve cupping, nasopharyngitis, deafness, vertigo, eczema,…

Risk Factor (Pregnancy/Lactation)

Contraindications: Ocular or periocular infection. Precautions: Monitor intra-ocular pressure following injection; Pregnancy; breast-feeding.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.