Norethisterone Oenanthate and Estradiol Valerate

Contraceptive · Oestrogen/Progestogen

Indications

Hormonal contraception.

Dosage

Adults: Inj 1 mL IM (deep) on the first day of a cycle. Then inj are to be given, regardless of the cycle pattern, at intervals of 30 (plus minus 3 days) i.e., minimum 27, max 33 days. If the injection interval is more than 33 days, no adequate contraception cover will be available that time onwards.

Adverse Effects

Headache, GI upset, nausea, a feeling of tension in the breasts, body weight changes and libido, depressive moods. Rarely breakthrough bleeding (discontinue if heavy break-through bleeding) and amenorrhoea.

Risk Factor (Pregnancy/Lactation)

Contraindications: Pregnancy. Severe liver dysfunction, Dubin-Johnson syndrome, Rotor syndrome, liver tumour, thromboembolic processes in arteries or veins, sickle cell anaemia, cancer of breast, endometrium, severe diabetes, disturbances of lipometabolism, history of herpes pregnancy, otosclerosis with deterioration. Precautions: Use of injectable hormonal contraceptive requires same precautions as applicable for combined oral contraceptives (Pill).

Interactions

Barbiturates, phenylbutazone, hydantoins, rifampicin, ampicillin, oral antidiabetics, insulin.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.