Neomycin, Polymyxin B, Bacitracin and Lignocaine, Topical

Antibacterial · Aminoglycoside/Antibacterial/Antibiotic/Local anaesthetic

Indications

First aid to help prevent infection and temporarily relieve pain in minor burns, cuts, nicks, scrapes, scratches and abrasions.

Dosage

Adults & Children: Clean the affected area. Apply a small amount on the affected area 1 to 3 times daily. Cover the affected area with a sterile bandage, if desired.

Adverse Effects

Nephrotoxicity, sensitization.

Risk Factor (Pregnancy/Lactation)

Precautions: Large open wounds.

Advice to Patient

Discontinue immediately and contact prescriber if there is rash or allergic reaction or if there is no improvement or worsening of condition. Avoid contact with eye, eyelids, fingers.

Pharmacokinetics

NEOMYCIN :Absorption: Not absorbed through intact skin. It may be absorbed from wounds, burns, or skin ulcers. Metabolism: Not metabolized. POLYMYXIN B: Absorption: Not absorbed through mucous membranes, or intact or denuded skin. Half-life elimination: 6 hrs. Prolonged in renal impairment. Excretion: Urine (60% of a dose). BACITRACIN: Absorption: Not well-absorbed from intact or denuded skin, wounds, or mucous membranes. LIGNOCAINE: Absorption: Readily absorbed from mucous membranes and through damaged skin. Poor absorption through intact skin. Metabolism: Hepatic. Bioavailability: 3%. Excretion: Urine.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.