Mirogabalin
Non-narcotic Analgesic · Gabapentinoids
Indications
Peripheral neuropathic pain in adults.
Dosage
Adults: Initially, 5 mg twice daily. Increase the dose by 5 mg/dosing with an interval of at least 1 wk up to 15 mg twice daily. Dose may be increased or decreased between 10 mg and 15 mg twice daily, based on patient’s age or symptoms. Max: 15 mg twice daily. Children: Not recommended.
Adverse Effects
Somnolence, dizziness, peripheral oedema, weight gain.
Risk Factor (Pregnancy/Lactation)
Pregnancy: Positive evidence of risk: Use only when no safer alternative exists for a serious problem. Lactation: Caution advised or effect undetermined. Precautions: Renal impairment. Elderly. Do not stop the medication abruptly, gradually decrease the dose and then stop.
Interactions
Probenecid. Cimetidine. Lorazepam.
Advice to Patient
Take with or without meals. Do not drive vehicles, operate machinery or carry out tasks that require mental alertness during treatment.
Pharmacokinetics
Absorption: Rapid. Metabolism: Hepatic (13-20%). Renal. Half-life elimination: 2-3 hrs. Time to peak: 1 hr. Excretion: Urine (99%). Faeces (1%).
Brands with this active ingredient
Compiled by Healify Pharmacy from published drug references. How we compile it →
Always consult a pharmacist or doctor.