Miltefosine
Cytostatic · Phospholipid derivative
Indications
Visceral leishmaniasis.
Dosage
Adults: 50-150 mg daily for 28 days.
Advice to Patient
Take with meals. Do not chew, crush or open capsules, swallow whole. Take plenty of water during treatment. Contact prescriber if there is severe nausea, vomiting, diarrhoea, unusual bruising or bleeding, painful or difficult urination, swelling in feet/ankles, unusual tiredness, stomach pain, yellowing of white parts of eye, swelling on face/tongue, red or purple skin rash, sore throat.
Pharmacokinetics
Absorption: Slowly absorbed from the GI tract. Metabolism: Hepatic. Half-life elimination: 7 days. Terminal: 31 days. Time to peak, plasma: 7 hrs. Excretion: Urine (<0.2%).
Compiled by Healify Pharmacy from published drug references. How we compile it →
Always consult a pharmacist or doctor.