Meclizine and Vitamin B6
Antiemetic & Gastroprokinetic · Piperazine derivative/Vitamin
Indications
Prophylaxis and treatment of nausea and vomiting in pregnancy.
Dosage
Adults: Once a day, 1 or 2 tab at bedtime. Children: Not recommended.
Risk Factor (Pregnancy/Lactation)
Pregnancy: No evidence of risk in humans. Lactation: Contraindicated or not recommended.
Pharmacokinetics
MECLIZINE: Onset: Oral: 1 hr. Duration: Oral: 8-24 hr. Absorption: Well absorbed. Metabolism: Hepatic. Half-life elimination: 5-6 hrs. Time to peak, plasma: 1.5-6 hrs. Excretion: Urine (as metabolites). Faeces (as unchanged drug). VITAMIN B6: Absorption: Readily absorbed from the GI tract. Metabolism: Hepatic. Half-life elimination: 15-20 days. Time to peak: 5.5 hrs. Excretion: Urine.
Compiled by Healify Pharmacy from published drug references. How we compile it →
Always consult a pharmacist or doctor.