Mebeverine and Ispaghula Husk

Antispasmodic & Anticholinergic · Antispasmodic/Bulking agent

Indications

Gastro-intestinal spasm. IBS.

Dosage

Adults: 1 sachet three times daily 20 min before meals. Adequate fluid intake should be maintained. Children: Not recommended.

Adverse Effects

Allergic reactions.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Risk cannot be ruled out. Contraindications: Paralytic ileus. Intestinal obstruction and colonic atony. Severe renal or cardiovascular conditions Precautions: Porphyria.

Pharmacokinetics

MEBEVERINE: Absorption: Oral: Rapid and complete. Metabolism: Via hydrolysis. The main metabolite in plasma is DMAC (Demethylated carboxylic acid). Half-life elimination: DMAC: 5.77 hrs. Time to peak, plasma: 1-3 hrs. Excretion: Urine. ISPAGHULA HUSK: Absorption: Acts locally (it has physical mode of action). Not absorbed. Metabolism: Not metabolized. Excretion: Faeces.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.