Mebeverine

Antispasmodic & Anticholinergic · Antispasmodic

Indications

Gastro-intestinal spasm. IBS.

Dosage

TABLET: GI Spasm/IBS: Adults: 1 tab three times daily 20 min before meals. Children: Not recommended. CAPSULE: IBS: Adults: 1 cap twice daily 20 min before meals. Children: Not recommended. ORAL SOLN: IBS: Adults: 1-2 tsp twice daily 20 min before meals. Children: Not recommended.

Adverse Effects

Allergic reactions.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Paralytic ileus. Precautions: Porphyria.

Advice to Patient

Take 20 minutes before meals.

Pharmacokinetics

Absorption: Oral: Rapid and complete. Metabolism: Via hydrolysis. The main metabolite in plasma is DMAC (Demethylated carboxylic acid). Half-life elimination: DMAC: 5.77 hrs. Time to peak, plasma: 1-3 hrs. Excretion: Urine.

Unlicensed Use

Children: Adjunct in gastro-intestinal disorders characterised by smooth muscle spasm: To be taken preferably 20 minutes before meals. 3-4 yr, 25 mg 3 times daily; 4-8 yr, 50 mg 3 times daily; 8-10 yr, 100 mg 3 times daily; 10-18 yr, 135-150 mg 3 times daily.

Brands with this active ingredient

• Avemeb
• Baver
• Bevrin
• Biospa
• Caborin
• Colief
• Coliver
• Colofac
• Colonil
• Colorin
• Colospas
• Colospas Fibro
• Conrine
• Curaverine
• Despas

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.