Lornoxicam

Anti-rheumatic, Systemic · Oxicam

Indications

Musculoskeletal and joint disorders such as osteoarthritis and rheumatoid arthritis. Post-operative pain.

Dosage

Osteoarthritis and rheumatoid arthritis: Adults: 12 mg daily. Pain: Adults: 8-16 mg daily. Children: Not recommended.

Adverse Effects

GI perforation, ulceration, bleeding or upset; monitor patient. Muco-cutaneous reactions including pruritus, rash, urticaria, angioedema, photosensitivity, erythema multiforme, Stevens-Johnson syndrome. CNS or cardiovascular effects, blood dyscrasias, transient disturbances in liver tests. Headache, GI upset, fluid and electrolyte disturbances.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Positive evidence of risk: Use only when no safer alternative exists for a serious problem. Lactation: Caution advised or effect undetermined. Contraindications: Aspirin/anti-inflammatory induced allergy. Active peptic ulcer, history of recurrent ulceration. Precautions: Severe cardiac insufficiency, hypovolaemia, dehydration, confirmed or suspected cerebrovascular bleeding. Haemorrhagic diathesis, operations with a risk of haemorrhage or incomplete haemostasis.

Interactions

Cimetidine. Anticoagulants, other NSAIDs, hypoglycaemics.

Advice to Patient

Take with meals. Contact prescriber if there is severe nausea, vomiting, dizziness, drowsiness, muscle pain, diarrhoea, constipation, lack of sleep, dry mouth, stomach pain, depression, increased sleepiness.

Pharmacokinetics

Absorption: Absorbed rapidly and almost completely from the GI tract. Metabolism: Hepatic. Half-life elimination: 3-5 hrs. Excretion: Urine. Faeces (mainly).

Brands with this active ingredient

• Acabel
• Atcam
• Cam E
• Camflex
• Cammi
• Caracam
• Clorten
• Flexilor
• Hinocam
• Intelgesic
• Kanlor
• L-Nox
• Larkin
• Leenor
• Leenor Plus

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.