Levonorgestrel, IUS

Contraceptive · Progestogen

Indications

Contraception. Idiopathic menorrhagia.

Dosage

Contraception: Adults: To be inserted into the uterine cavity within 7 days of the onset of menstruation. Replace after 5 yr. Delay postpartum use until 6 wk after delivery. Idiopathic menorrhagia: Adults: To be inserted into the uterine cavity within 7 days of the onset of menstruation. Remove if significant reduction in blood loss is not achieved in 3-6 mth. Replace after 5 yr. Delay postpartum use until 6 wk after delivery.

Adverse Effects

Altered menstrual patterns, headache, lower abdominal pain, back pain, skin disorders, vaginal discharge, mastalgia, vaginitis, mood changes, nausea, oedema, ovarian cysts, pelvic inflammatory disease, weight gain, hair loss, greasy hair. Delayed follicular atresia; monitor with ultrasound.

Risk Factor (Pregnancy/Lactation)

Contraindications: Pregnancy, undiagnosed genital bleeding, uterine abnormality, genital infection, current or recurrent pelvic inflammatory disease, postpartum endometritis disease, postpartum endometritis, infected abortion, cervicitis, cervical dysplasia, uterine or cervical malignancy, history of bacterial endocarditis or severe pelvic infection in women with an anatomical heart lesion or valve replacement, severe arterial disease, liver tumour, liver disease, increased susceptibility to infections, blood malignancy, leukaemia, recent trophoblastic disease. Precautions: Hormone dependent neoplasia, liver, arterial, thromboembolic and cardiac valve disease, diabetes, chronic corticosteroid therapy, unusually severe headaches. History of ovarian cysts or ectopic pregnancy, lactation. Remove with recurrent endometritis, pelvic infection, severe acute infection, partial expulsion,…

Interactions

Liver enzyme inducing drugs.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.