Lactulose, Lactose and Galactose

Laxative · Lipase inhibitor/Osmotic laxative

Indications

Constipation. Hepatic encephalopathy.

Dosage

Constipation: Adults: Initially 15 mL twice daily. Children: Under 1 yr, 2.5 mL; 1-4 yr, 5 mL; 5-10 yr, 10 mL. All twice daily. Encephalopathy: Adults: Initially 30-50 mL three times daily; adjust dose to produce 2 or 3 soft stools daily.

Risk Factor (Pregnancy/Lactation)

Pregnancy: No evidence of risk in humans. Lactation: Caution advised or effect undetermined. Contraindications: Galactosaemia, intestinal obstruction.

Pharmacokinetics

LACTULOSE: Onset: Constipation: Up to 24-48 hrs to produce a normal bowel movement. Encephalopathy: At least 24-48 hrs. Absorption: Poor. Metabolism: Via colonic flora. Excretion: Primarily faeces, urine (=3%).

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.