Ketotifen, Oral

Bronchodilator & Anti-asthma Preps: Orals/Parenterals · H1 receptor antagonist

Indications

Prophylaxis of bronchial asthma. Allergic conditions.

Dosage

Adults: 1-2 mg twice daily with food. Children: Under 2 yr, not recommended; over 2 yr, 1 mg twice daily with food.

Adverse Effects

Drowsiness, impaired reactions, dry mouth, dizziness. Occasionally, CNS stimulation, wt gain, isolated severe skin reactions. Rarely, cystitis, raised liver enzymes, hepatitis.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Precautions: History of epilepsy. Withdraw over 2-4 weeks in asthma patients.

Interactions

Alcohol, CNS depressants, oral hypoglycaemics, antihistamines.

Advice to Patient

Take with meals.

Pharmacokinetics

Absorption: Almost completely absorbed from the GI tract. Metabolism: Hepatic (extensive first-pass). Bioavailability: 50%. Half-life elimination: Terminal: 21 hrs. Time to peak, plasma: Oral: 2-4 hrs. Excretion: Urine.

Brands with this active ingredient

• Aktofen
• Antifen
• Aria
• Asfen
• Asmarax
• Asmofen
• Asperfin
• Asthacure
• Asthanil
• Asthonex
• Asthotifen
• Bronfit
• Gratifen
• Ketoplus
• Ketoresp

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.