Indacaterol, Glycopyrronium And Mometasone

Bronchodilator & Anti-asthma Preps: Inhalants · Antimuscarinic/Beta-2 agonist/Corticosteroid

Indications

M-Cap: Maintenance treatment of asthma not adequately controlled with a maintenance combination of a long-acting beta2-agonist and a medium or high dose of an inhaled corticosteroid who experienced one or more asthma exacerbations in the previous 12 months.

Dosage

M-Cap: Adults: One capsule to be inhaled daily. Administer at the same time each day. After inhalation, rinse mouth with water without swallowing. Max: 150/50/160 mcg once daily. Children: Not recommended.

Adverse Effects

M-Cap: Nasopharyngitis, asthma (exacerbation), upper respiratory tract infection, candidiasis, urinary tract infection, hyperglycaemia, headache, tachycardia, oropharyngeal pain, cough, dysphonia, gastroenteritis, musculoskeletal pain, muscle spasms, pyrexia.

Risk Factor (Pregnancy/Lactation)

Precautions: Pregnancy. Lactation.

Interactions

M-Cap: MAOIs, TCAs, methylxanthine derivatives, steroids, non-potassium-sparing diuretics, beta-blockers.

Pharmacokinetics

Bioavailability (absolute): Indaceterol: 45%. Glycopyrronium: 40%. Mometasone: <10%. Time to peak, plasma: Indacaterol: Approx. 15 mins. Glycopyrronium: 5 mins. Mometasone: 1 hr.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.