Gadoxetate Disodium

Diagnostic Aids & Test Preps · Diagnostic contrast media

Indications

Intravenous use in T1-weighted magnetic resonance imaging (MRI) of the liver to detect and characterize lesions in adults with known or suspected focal liver disease.

Dosage

Adults: IV: 0.1 mL/kg body wt. (0.0.25mmol/kg body wt.). Children: Not recommended.

Administration

Administer undiluted as a single intravenous bolus inj at a flow rate of approx. 2 mL/second. Flush the IV cannula with NS after the injection.

Adverse Effects

Headache, dizziness, dysgeusia, parosmia, increased blood pressure, flushing, respiratory disorders, vomiting, nausea, rash, pruritus, feeling hot.

Risk Factor (Pregnancy/Lactation)

Precautions: Severe renal impairment, acute kidney injury. Pregnancy. Lactation.

Interactions

Rifampicin.

Advice to Patient

Contact prescriber if you experience burning, itching, swelling, scaling, hardening and tightening of the skin; red or dark patches on the skin; stiffness in joints with trouble moving, bending or straightening the arms, hands, legs or feet; pain in the hip bones or ribs; or muscle weakness.

Pharmacokinetics

Metabolism: Not metabolized. Half-life elimination: 0.91-0.95 hrs. Excretion: Urine. Faeces.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.