Fluticasone Propionate and Mupirocin

Corticosteroid Combinations, Topical · Antibacterial/Corticosteroid

Indications

Inflammatory skin disorders such as dermatitis unresponsive to less potent corticosteroids.

Dosage

Adults & Children: Apply thinly 1-2 times daily.

Advice to Patient

For external use only. Do not cover or bandage the treated area unless recommended by the prescriber. Avoid medication contact with eyes. Do not use on face, underarms and groin areas. Contact prescriber if there is no improvement after 2 weeks.

Pharmacokinetics

FLUTICASONE PROPIONATE: Absorption: Topical absorption is very low. Inflammation and/or other disease processes in the skin increase percutaneous absorption. Occlusive dressings substantially increase the percutaneous absorption. Metabolism: Absorbed drug is metabolized hepatically. Excretion: Faeces (mainly). Urine (<5%). MUPIROCIN: Absorption: Small amounts are absorbed into the systemic circulation. Metabolism: Rapidly metabolized to monic acid. Half-life elimination: Mupirocin: 20-40 mins. Monic acid: 30-80 mins. Excretion: Urine.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.