Fluticasone Propionate

Nasal Preparations · Corticosteroid

Indications

Seasonal allergic rhinitis, perennial rhinitis.

Dosage

Adults: 2 sprays in each nostril once daily in the morning. Maintenance, 1 spray in each nostril once daily, use minimum effective dose. Max 4 sprays in each nostril daily. Children: Under 4 yr, not recommended; 4-11 yr, 1 spray in each nostril once daily in the morning; max 2 sprays in each nostril daily.

Adverse Effects

Nasal irritation, epistaxis, taste disturbances, hypersensitivity, headache. Rarely, septal perforation, nasal ulceration, bronchospasm, anaphylaxis.

Risk Factor (Pregnancy/Lactation)

Precautions: Treat nasal infections. Transferring from systemic steroids. Prolonged treatment with high doses increases risk of adrenal suppression and systemic effects. Consider additional systemic steroids in stress or surgery. Monitor height of children on prolonged therapy. Pregnancy, lactation.

Interactions

Potent inhibitors of CYP3A4.

Pharmacokinetics

Metabolism: Hepatic. Half-life elimination: Approx. 7.8 hrs. Time to peak: 1 hr.

Brands with this active ingredient

• Atcovate
• Cosvate
• Cutivate
• Cutivate M
• Flexosone
• Flixonase
• Flixotide
• Fluticamax
• Fluticort
• Flutiderm
• Flutinate
• Flutiprop Topical
• Flutizaf
• Flutrolz
• Forsonide

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.