Estradiol and Norethisterone Acetate

Contraceptive · Oestrogen/Progestogen

Indications

Oral contraception.

Dosage

Adults: 1 tab daily without break in medication, starting with tab from blue section of pack on 5th day of menses or at any time in cases of oligomenorrhoea. Children: Not applicable.

Adverse Effects

Nausea, vomiting, weight gain, breast tenderness & enlargement, withdrawal bleeding, sodium retention with oedema, liver function disorders, jaundice, rashes, chloasma, headache. Endometrial carcinoma in post-menopausal women.

Risk Factor (Pregnancy/Lactation)

Contraindications: History of, or predisposition to, thrombophlebitis, thromboembolic disorders, cerebrovascular disease. History of pruritus, during pregnancy deteriorating otosclerosis, idiopathic jaundice or pemphigoid gestations (herpes gestations). Impaired hepatic excretory function such as Dubin-Johnson & Rotor syndromes. Sickle cell anaemia. Acute or chronic liver disease, jaundice, porphyria, disorders of lipid metabolism. Oestrogen dependent carcinomas, endometriosis, undiagnosed genital bleeding. Pregnancy. Lactation. Precautions: Hypertension, myocardial or renal disease, asthma, varicose veins, epilepsy, chloasma, uterine fibromyomata. Examine BP, pelvic organs & breasts before & regularly during treatment.

Interactions

Diuretics, antihypertensives, liver enzyme inducing drugs.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.