Doxofylline

Bronchodilator & Anti-asthma Preps: Orals/Parenterals · Xanthine

Indications

Bronchospasm in asthma and chronic bronchitis.

Dosage

TAB: Adults: 400 mg 2-3 times daily. SYP: Children: 6-12 yr, 1 tsp 2-3 times daily. Under 6 yr, not recommended.

Adverse Effects

Tachycardia, nausea, Gl distress, headache, insomnia, arrhythmias.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Risk cannot be ruled out. Lactation: Caution advised or effect undetermined. Precautions: Cardiac or liver disease. Peptic ulceration.

Interactions

Cimetidine, erythromycin, ciprofloxacin, interferon.

Advice to Patient

Take with or without meals.

Pharmacokinetics

Metabolism: Hepatic. Bioavailability: 63 ± 25%. Half-life elimination: IV: 1.83 ± 0.37 hrs. Oral: 7.01 ± 0.8 hrs. Time to peak, plasma: 1.19 ± 0.19 hrs. Excretion: Urine.

Brands with this active ingredient

• Agolix
• Brofyl
• Deline
• Dolenex
• Dowfylin
• Doxfree
• Doxlin
• Doxofam
• Doxofilina
• Doxofyl
• Doxolin
• Flyod
• Fylod
• Fyoxlin
• Kemyfylin

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.