Dexamethasone and Chloramphenicol, Eye

Corticosteroid Combinations, Eye · Chloramphenicol/Corticosteroid

Indications

Infected ocular inflammation.

Dosage

DROP: Adults & Children: 1-2 drops four to six times daily. OINT: Adults & Children: Apply three to four times daily.

Risk Factor (Pregnancy/Lactation)

Contraindications: Viral, fungal, tuberculous or purulent infections. Glaucoma. Soft contact lenses. Precautions: Prolonged use in pregnancy or infants.

Advice to Patient

Wash hands properly before use. To instill medication into eyes, tilt head back, look upward, instill drops or apply thin layer of ointment inside lower eyelid. Close eye and roll eyeball in all directions. Do not blink for 30 seconds. Apply gentle pressure to inner corner of eye for 30 seconds. Contact prescriber if there is eye pain, changes in vision, no improvement or worsening of condition. Avoid touching tip of applicator with eye. Avoid prolonged use. Do not use any other eye preparation for atleast 10 minutes. Do not share medication with anyone else. Wear sunglasses when in sunlight to prevent photosensitivity.

Pharmacokinetics

DEXAMETHASONE: Absorption: Well-absorbed. CHLORAMPHENICOL: Absorption: Well absorbed. Metabolism: Hepatic. Half-life elimination: Adults (normal hepatic and renal function): 1.5-3.5 hrs. Impaired renal function: 3-4 hrs. Severely impaired hepatic function: 4.6-11.6 hrs. Children (1 mth-16 yrs): 3-6.5 hrs. Infants 1-2 days old: 24 hrs or longer and is highly variable, esp in low birth-wt infants.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.