Cefadroxil
Cephalosporin · Cephalosporin
Indications
Infections of respiratory tract, urinary tract and skin by susceptible organisms.
Dosage
Adults: 500 mg-1 gm twice daily or 1 gm once daily or 2 gm daily in two divided doses. Children: Under 1 yr, 25 mg/kg daily in divided doses; 1-6 yr, 250 mg twice daily; over 6 yr, 500 mg twice daily. Upper Respiratory Infection: Adults: 1 gm once daily or 500 mg twice daily for 10 days. Children: 15 mg/kg every 12 hr or 30 mg/kg daily. Urinary Tract Infection: Adults: Uncomplicated Lower UTI: 1-2 gm/day given once daily or in two divided dose. Other UTIs: 1 gm twice daily. Children: 15 mg/kg every 12 hr. Skin Infection: Adults: 1 gm once daily or 500 mg twice daily. Children: 15 mg/kg every 12 hr (or 30 mg/kg once daily for impetigo).
Adverse Effects
Hypersensitivity reactions. Gl disturbances. Pseudomembranous colitis, haemolytic anaemia.
Risk Factor (Pregnancy/Lactation)
Pregnancy: No evidence of risk in humans. Lactation: Caution advised or effect undetermined. Precautions: Renal impairment. Hypersensitivity to penicillins. History of GI disturbance, severe allergy or asthma.
Interactions
Loop diuretics, anticoagulants, other antibiotics, antiplatelets, colestyramine.
Advice to Patient
Do not chew or crush extended release tablets. Contact prescriber if there is pain on urination, changes in urinary pattern, vaginal drainage, vaginal itching, mouth sores, foul-smelling bloody stool, bloody urine, unusual chills or fever, nausea, vomiting, abdominal pain, furry tongue occur. Watery or bloody stools can occur 2 or more months after therapy and can be serious, requiring immediate treatment.
Pharmacokinetics
Absorption: Rapid and well absorbed from GI tract. Half-life elimination: 1-2 hrs; Renal failure: 20-24 hrs. Time to peak serum concentration: Within 70-90 mins. Excretion: Urine.
Brands with this active ingredient
Compiled by Healify Pharmacy from published drug references. How we compile it →
Always consult a pharmacist or doctor.