Betamethasone Valerate, Gentamicin and Miconazole, Topical

Corticosteroid Combinations, Topical · Aminoglycoside/Corticosteroid/Imidazole antifungal

Indications

Inflammatory skin conditions involving fungi.

Dosage

Adults & Children: Apply thinly 1-2 times daily.

Advice to Patient

Wash and dry the skin before applying. Apply a thin film to cover affected areas and rub gently. Wash hands thoroughly after applying, unless hands are the area being treated. If a dose is missed, apply it as soon as you remember unless it is almost time for the next dose. Do not apply double dose. Contact prescriber if there is burning, itching, or irritation of the skin, dryness, increased redness or scaling of the skin. Do not apply for more than prescribed period of time. Cover the treated area as recommended by the prescriber.

Pharmacokinetics

BETAMETHASONE VALERATE: Absorption: It ranges from about 1% in areas with a thick stratum corneum to as high as 36% in areas with a thin stratum corneum. Absorption increases in areas of skin damage, inflammation, or occlusion. Some systemic absorption of topical steroids occurs. Metabolism: After topical administration, drug is metabolized primarily in skin. The small amount absorbed into systemic circulation is metabolized hepatically. Excretion: Renal (inactive metabolites). Faeces (small amounts of metabolites). GENTAMICIN: Absorption: Readily absorbed from large burnt, denuded or granulating areas but not through intact skin. Faster and greater absorption with the cream compared to the ointment. Metabolism: Not metabolized. Half-life elimination: Adults: 2-3 hrs. Severe renal impairment: 24-60 hrs. Excretion: Urine. MICONAZOLE: Absorption: Little absorption through skin or mucous…

Brands with this active ingredient

• Micogen-B
• Mycona-GB

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.