Betamethasone Dipropionate and Salicylic Acid, Topical

Corticosteroid Combinations, Topical · Antiseptic/Corticosteroid

Indications

Psoriasis & other scaly skin disorders.

Dosage

Adults & Children: Apply sparingly two or three times daily.

Adverse Effects

Cushingoid changes, adrenal suppression, local skin reactions, acne, atrophy, striae, telangiectasia, mild pigmentation, hypertrichosis, pruritus, folliculitis. Hypersensitivity reactions incl contact dermatitis (discontinue).

Risk Factor (Pregnancy/Lactation)

Contraindications: Untreated bacterial, fungal or viral infections or parasitic infestations, use on burns, acne or rosacea, perioral dermatitis, widespread plaque psoriasis, perianal or genital pruritus, pruritus without inflammation. Precautions: Do not use potent steroids to treat diaper dermatoses in infants. Avoid extensive or prolonged use (limit to max 7 days in children). If using potent steroids in children or on face, limit to 5 days and avoid occlusion. Avoid mucous membranes and eye area. Broken, inflamed or occluded skin, psoriasis, dermatitis around chronic leg ulcers. Risk of visual disturbances. Elderly.

Advice to Patient

Apply a thin film to cover affected areas and rub gently. Do not wash the affected area for several hours after applying the lotion. If a dose is missed, apply it as soon as you remember, unless it is almost time for the next dose. Do not apply double dose. Do not apply for more than prescribed period of time. Do not bandage, wrap or cover the treated area unless advised by the prescriber. Avoid contact of medication with eyes. In case of contact, wipe off the medication and rinse thoroughly with water.

Pharmacokinetics

BETAMETHASONE DIPROPIONATE: Absorption: It ranges from about 1% in areas with a thick stratum corneum to as high as 36% in areas with a thin stratum corneum. Absorption increases in areas of skin damage, inflammation, or occlusion. Some systemic absorption of topical steroids occurs. Metabolism: After topical administration, drug is metabolized primarily in skin. The small amount absorbed into systemic circulation is metabolized hepatically. Excretion: Renal (inactive metabolites). Faeces (small amounts of metabolites). SALICYLIC ACID: Absorption: Readily absorbed through the skin. Time to peak, serum: 5 hrs. Excretion: Urine.

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.