Aluminium Hydroxide, Magnesium Hydroxide and Simethicone

Antacid, Antiflatulent · Antacid/Antiflatulent

Indications

Peptic ulcer, hiatus hernia, acute and chronic recurrent gastritis, dyspepsia, all other forms of gastric hyperacidity and flatulence.

Dosage

Tab: Adults: 1-2 tab chewed or sucked after meals or when required. Children: Over 6 yr, half adult dose; Under 6 yr, not recommended. Susp: Adults: 1-2 tsp between meals and at bed time. Children: Over 12 yr, same as adult dose; 5-12 yr, half adult dose.

Adverse Effects

Diarrhoea, constipation, vomiting, nausea, intestinal obstruction (large dose).

Risk Factor (Pregnancy/Lactation)

Pregnancy: Risk cannot be ruled out. Lactation: Caution advised or effect undetermined. Precautions: Low phosphate diet, renal impairment.

Interactions

May alter absorption of tetracyclines, Fe salts, H2-receptor antagonists, INH, warfarin, quinidine.

Pharmacokinetics

ALUMINIUM HYDROXIDE: Onset of action: Variable. Duration: 20-80 mins. Absorption: Minimal absorption. Small amounts may be absorbed systemically. Excretion: Faeces. MAGNESIUM HYDROXIDE: Onset of action: 0.5-3 hrs. Duration: Variable. Absorption: About 15%-50% is absorbed very slowly through the small intestine. Metabolism: Does not undergo metabolism. Excretion: Urine (absorbed portion of drug). Faeces, saliva (unabsorbed portion of drug). SIMETHICONE: Absorption: Not absorbed into the blood stream. Metabolism: Not metabolized. Bioavailability: None. Excretion: Excreted unchanged in faeces.

Brands with this active ingredient

• Almacid
• Almagel
• Almasim
• Alunmag Plus
• Alupep
• Amrocon
• Colenticon
• Deacid
• Dijex MP
• Dimeco
• Gas-X
• Gelcid
• Gelusil
• Geocone
• Infacol Plus

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.