Aluminium Hydroxide and Magnesium Trisilicate

Antacid, Antiflatulent · Antacid

Indications

Peptic ulcer, hiatus hernia, acute and chronic recurrent gastritis, dyspepsia, all other forms of gastric hyperacidity and flatulence.

Dosage

Tab: Adults: 1-2 tab chewed or sucked after meals or when required. Children: Over 6 yr, half adult dose; under 6 yr, not recommended.

Adverse Effects

Constipation, diarrhoea.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Risk cannot be ruled out. Lactation: Caution advised or effect undetermined. Precautions: Impaired renal function, low phosphate diet.

Interactions

Tetracyclines, INH, Fe salts, warfarin, digoxin.

Pharmacokinetics

ALUMINIUM HYDROXIDE: Onset of action: Variable. Duration: 20-80 mins. Absorption: Minimal absorption. Small amounts may be absorbed systemically. Excretion: Faeces. MAGNESIUM TRISILICATE: Absorption: The hydrated silicon dioxide is formed in the stomach and passes into the intestinal track where, silica can be partly absorbed. Half-life elimination: 16-20 hrs. Excretion: Urine (30%). Faeces (70%).

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.