Aceclofenac, Inj/Oral

Anti-rheumatic, Systemic · Phenylacetic acid

Indications

Osteoarthritis, rheumatoid arthritis, ankylosing spondylitis.

Dosage

Tab: Adults: 100 mg morning and evening. Children: Not recommended. Inj: 150 mg once or twice daily for five days.

Adverse Effects

GI upset, dizziness, increased hepatic enzymes, pruritus.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Peptic ulceration, GI bleeding, moderate to severe renal or hepatic impairment, severe cardiac, aspirin/anti-inflammatory induced allergy, bleeding disorders, ischaemic heart disease, cerebrovascular disease, peripheral arterial disease, CHF, varicella. Precautions: GI disease. Renal, hepatic or cardiac impairment, asthma, hypertension, CHF, cardiovascular risk factors, haematological abnormalities, SLE and mixed connective tissue disorders, porphyria, recent major surgery. Monitor renal and hepatic function and blood counts during long term treatment. Use lowest effective dose for shortest duration. Elderly.

Interactions

Lithium, digoxin, diuretics, other NSAIDS, corticosteroids, cyclosporin, quinolone antibiotics, antidiabetics, methotrexate, SSRIs, antiplatelets, antihypertensives, mifepristone, tacrolimus, zidovudine, hypoglycaemic agents.

Pharmacokinetics

Absorption: Well absorbed from the GI tract. Half-life elimination: 4 hrs. Time to peak, plasma: Oral: 1-3 hrs. Excretion: Urine (2/3rd of dose). Faeces (20%).

Brands with this active ingredient

• Acanef
• Aceclocare
• Acecol
• Acefen
• Aceford
• Acelak
• Acelish
• Acelo
• Acemed
• Acenac
• Acenim
• Acer
• Aceroc
• Aczofena
• Afenac

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.